APASL STC & BUILD 3.0 PROGRAM
Held On: 7th-9th Feb, 2025
SESSION I - MASH/MAFLD CIRRHOSIS
- The liver-heart axis interplay in MASH cirrhosis: Current understanding and targets for therapy
- Targeting mechanisms of cell death (apoptosis, necroptosis, pyroptosis and ferroptosis) in MASH/MAFLD
- Neuro-cognitive decline in MASLD: Hepatologist’s perspective and implications for management
SESSION II- A. RARELY DISCUSSED HEPATOLOGY
- Pharmacotherapy, reversibility and monitoring response to therapy in PoPH
- Drug – drug interactions in hepatology wards & ICU
- Can alcoholic liver disease be cured by gene therapy?
- Pitfalls in diagnosis of TTP and HLH in critically ill liver disease patients
SESSION II- B. RARELY DISCUSSED HEPATOLOGY
- Assessment of concomitant non-liver alcohol syndromes in patients with ALD and their impact on outcomes
- Contrast nephron interaction in decompensated cirrhosis : Biomarkers of injury and therapeutic targets
- Recent advances in management of hepatobiliary parasitic disorders
- Expert Chat and wrap-up of the first & second sessions
SESSION - III : PORTAL HT
- Clinical decision making in pre-emptive TIPS : Setting the goal post and the boundaries
- Chylous ascites in DCLD: pathophysiology & current and emerging therapeutics
- Reversibility of portal hypertension: Newer strategies
- Experts chat & discussion
SESSION IV- A. END POINTS IN CRITICAL CARE (HEPATOLOGY)
- Case snippets based panel discussion : Role of Lactates, ammonia, base excess etc in day to day ICU management of liver diseases
- Use of albumin in the ICU : The yeahs and the nays
- Indications to terminate CRRT with improvement and worsening of patient?
- PLEX in ICU: challenges, contraindications, futility and when to terminate?
- Current prognostic tools in critically ill cirrhotic: what we have and what do we need?
- Early diagnosis of vasoconstrictor non-responder: definitions, tools and implications
- Expert wrap-up
SESSION IV- B. END POINTS IN CRITICAL CARE (HEPATOLOGY)
-
Case snippets based coagulopathy management in ICU
A. Prior to elective ICU procedures (lines, HD caths, tappings, tracheostomy etc)
B. IC bleed, Blood in ET, Bleeding from around lines
C. Diffuse mucosal bleeds - Special filters in liver disease: current evidence and what is on the horizon?
- Principles and indications of current liver assist devices: what we have and what are we lacking ?
- Expert comment & discussion
- DINNER SYMPOSIUM- Multiomic algorithms in ICU: Bench to bedside
SESSION V - ACLF
- Impact of interventions in pre-ACLF and early stages of ACLF
- Case based panel discussion: ACLF-2&3 now out of ICU
- Improving transplant free survivals in CTP-C decompensated cirrhosis
SESSION VI - LIVER REGENERATION
- Concept of regenerative hepatology and its clinical applications
- Stem cells therapy in DCLD where are we and what is in future?
- Hepatocyte transplant, BAL, bioengineered mass and other emerging regeneration techniques
SESSION VII - QUALITY OF LIFE & PALLIATIVE CARE ISSUES
- Newly diagnosed decompensated cirrhosis in geriatric population: Unique issues and Solutions
- Principles of Ethical and moral dilemmas in management of end stage liver disease
- Management of morbidly obese advanced cirrhosis
- Case snippets based panel discussion : Ignored symptoms in liver disease cramps, insomnia, fatigue, erectile dysfunction etc
- Improving end of life care in terminal liver diseases
- APASL Guidelines on QOL and Palliative care in advanced liver disease
SESSION VIII - POT POURRI
- Approach to Recurrent fever in a advanced cirrhosis
- Management of mycobacterial infections in presence of advanced liver disease
- Case based discussion: White shadows on Xray chest, a clinical dilemma
SESSION IX - HCC
- Combination of different therapies: Can they really improve the outcome?
- Case based panel: A 7cm HCC with VP2 PVTT and CTP A5 compensated cirrhosis and PHT: Treatment options—Resection/TARE/Immuno/SBRT/Transplant
- Therapeutic options for oligometastasis in HCC
SESSION IV- B. END POINTS IN CRITICAL CARE (HEPATOLOGY)
-
Case snippets based coagulopathy management in ICU
A. Prior to elective ICU procedures (lines, HD caths, tappings, tracheostomy etc)
B. IC bleed, Blood in ET, Bleeding from around lines
C. Diffuse mucosal bleeds - Special filters in liver disease: current evidence and what is on the horizon?
- Principles and indications of current liver assist devices: what we have and what are we lacking ?
- Expert comment & discussion
- DINNER SYMPOSIUM- Multiomic algorithms in ICU: Bench to bedside
SESSION I
- Glucose metabolism in a steatotic liver: Implications for management
- Pharmacological management of obesity in 2025
- LDL subtypes and other lipid related emerging concepts in pathogenesis and management of MASLD
- Expert chat
SESSION II
- Case based discussion : Acute hepatitis with cholestasis & history of CAM in a young adult; Is it AIH, Wilsons Disease with CAM-DILI or seronegative hepatitis
- Debate: Liberalization of indications for treatment of HBV is the best way forward for patients with HBV
SESSION III
- Case based Panel discussion II: Refractory ascites with AKI-HRS on proteinuric CKD
- Radiomics and Radiogenomics: Is the future here?
- Genetic Cholestatic disorders in Adults
- Difficult to treat AIH
- EUS guided ablation of Liver tumors: Basics, tips and outcomes
- Experts chat and summary of the sessions 1 & 2
- How to plan for the inevitable
PARALLEL SYMPOSIUM: INFECTIONS IN CIRRHOSIS SATURDAY MORNING
- Cirrhosis associated immune dysfunction
- Vaccinations in cirrhosis: Which ones, how to administer and efficacy
- Rapid diagnostics (bio fires, BCID, Multiplex PCR etc) in cirrhosis: where to use and how?
- Accuracy and fallacies of other non-culture tests in diagnosis of bacterial and fungal infections in advanced cirrhosis
- Accuracy and fallacies of other non-culture tests in diagnosis of bacterial and fungal infections in advanced cirrhosis
- Assessing response to antibiotic therapy in patients with advanced liver diseases in ICU
- Emerging infections: New pathogens and changing susceptibility patterns
- Panel discussion: Management strategies for drug resistant organisms in cirrhosis
ENDOHEPATOLOGY WORKSHOP: HOW I DO IT?
Porto-systemic Collateral Management
- Endoscopic variceal band ligation
- Glue in esophageal and gastric varices
- EUS guided coil and glue for gastric varices
- Endoscopic management of duodenal, rectal and stomal varices
- EUS guided occlusion of porto-systemic shunts
Biliary and other diagnostic/therapeutic procedures in liver diseases
- Coagulation management prior to therapeutic procedures in liver diseases
- ERCP in liver diseases
- Cholangioscopy in PSC
- ERCP for portal biliopathy
- EUS guided liver biopsy
- EUS Portal pressure measurement
Other diagnostic and therapeutic procedures (Liver-IR interface)
What a hepatologist/gastroenterologist should know?
- BRTO/PARTO/CARTO
- Hepatic venous pressure gradient
- Transjugular liver biopsy
- TARE
- TACE
- RFA/MWA
SESSION IV - LEGENDS SPEAK
- Endoscopy in PSC : Indications, Techniques, Complications and Outcomes
- BUILD 2.0 Oration by Prof. Julia Wendon
- Is it time to change nomenclature from NCPF to PSVD
SESSION V - LEGENDS SPEAK
- BUILD 3.0 Oration by Prof K . Rajender Reddy
- Case based Panel Discussion - ACLF: ALD with acute HEV and myoglobinurea
- Recent advances in the prognostication and management strategies in alcoholic liver diseases
SESSION VI - B D PIMPARKAR ORATION BY PROF. PATRICK KAMATH
SESSION I
- Glucose metabolism in a steatotic liver: Implications for management
- Pharmacological management of obesity in 2025
- LDL subtypes and other lipid related emerging concepts in pathogenesis and management of MASLD
- Expert chat
SESSION II
- Case based discussion : Acute hepatitis with cholestasis & history of CAM in a young adult; Is it AIH, Wilsons Disease with CAM-DILI or seronegative hepatitis
- Debate: Liberalization of indications for treatment of HBV is the best way forward for patients with HBV
SESSION III
- Case based Panel discussion II: Refractory ascites with AKI-HRS on proteinuric CKD
- Radiomics and Radiogenomics: Is the future here?
- Genetic Cholestatic disorders in Adults
- Difficult to treat AIH
- EUS guided ablation of Liver tumors: Basics, tips and outcomes
- Experts chat and summary of the sessions 1 & 2
- How to plan for the inevitable
PARALLEL SYMPOSIUM: INFECTIONS IN CIRRHOSIS SATURDAY MORNING
- Cirrhosis associated immune dysfunction
- Vaccinations in cirrhosis: Which ones, how to administer and efficacy
- Rapid diagnostics (bio fires, BCID, Multiplex PCR etc) in cirrhosis: where to use and how?
- Accuracy and fallacies of other non-culture tests in diagnosis of bacterial and fungal infections in advanced cirrhosis
- Accuracy and fallacies of other non-culture tests in diagnosis of bacterial and fungal infections in advanced cirrhosis
- Assessing response to antibiotic therapy in patients with advanced liver diseases in ICU
- Emerging infections: New pathogens and changing susceptibility patterns
- Panel discussion: Management strategies for drug resistant organisms in cirrhosis
SESSION IV - LEGENDS SPEAK
- Endoscopy in PSC : Indications, Techniques, Complications and Outcomes
- BUILD 2.0 Oration by Prof. Julia Wendon
- Is it time to change nomenclature from NCPF to PSVD
SESSION V - LEGENDS SPEAK
- BUILD 3.0 Oration by Prof K . Rajender Reddy
- Case based Panel Discussion - ACLF: ALD with acute HEV and myoglobinurea
- Recent advances in the prognostication and management strategies in alcoholic liver diseases
